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Filtered Search Results
Medchemexpress LLC 2-(2,3-dihydro-1,3,6-trimethyl-2-oxo-1H-benzimidazol-5-yl)-6-(3-hydroxypropyl)-1H-benz[de]i | 2080306-23-4 | ≥98.0% | 429.5 Da | C25H23N3O4 | 100 MG
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BAY-299 is a small-molecule chemical probe that potently inhibits bromodomain-containing proteins, primarily BRPF2 (BRD1) and TAF1 family bromodomains. It is intended for research use in biochemical and cellular assays to probe bromodomain function, validate targets, and investigate chromatin-mediated transcriptional regulation. The compound is supplied as a solid with high purity suitable for laboratory studies.
- Potent biochemical inhibition of BRPF2 and TAF1 family bromodomains.
- Reported IC50 values: BRPF2 BD - 67 nM; TAF1 BD2 - 8 nM; TAF1L BD2 - 106 nM.
- Suitable for target validation and mechanistic studies in epigenetics.
- High purity (≥98%) for reliable assay performance.
- Molecular weight 429.5 Da and chemical formula C25H23N3O4.
- Supplied as a solid for routine laboratory handling.
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DSI LLC SO DR-SHAFT, SA: 2.00 PH_SLC,x_SDC
SO DR-SHAFT, SA: 2.00 PH_SLC,x_SDC
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eMolecules 5855-79-8 | 3-Amino-5-sulfobenzoic acid | Combi-Blocks | MFCD01825295 | 217.200 | C7H7NO5S | 95.000 | Nc1cc(cc(c1)S(O)(=O)=O)C(O)=O | 1g | 482930410
3-Amino-5-sulfobenzoic acid | Combi-Blocks | 5855-79-8 | MFCD01825295 | 217.200 | C7H7NO5S | 95.000 | Nc1cc(cc(c1)S(O)(=O)=O)C(O)=O | 1g | 482930410
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Apexbio Technology LLC CX-4945 sodium salt 1309357-15-0 50mg
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CX-4945 sodium salt (Silmitasertib sodium salt CAS 1309357-15-0) is a potent and selective inhibitor of casein kinase 2 (CK2) effectively targeting both the CK2 and CK2 catalytic subunits By inhibiting CK2 activity CX-4945 disrupts signaling pathways involved in cell cycle progression transcriptional regulation and cell survival The compound exhibits oral bioavailability and is widely utilized in research focused on tumor biology mechanistic studies of signaling cascades and the functional characterization of protein kinases
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Cayman Chemical NADP sodium salt hydrate
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The oxidized form of NADPH; serves as a cofactor in various biological reactions
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Cayman Chemical Fluvastatin sodium salt hydr
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An HMG-CoA reductase inhibitor (Ki = 0.3 nM for the rat enzyme); inhibits CYP2C9 (IC50 = 100 nM); inhibits oxidized LDL-induced ferroptosis and reverses oxidized LDL-induced decreases in GPX4 and system Xc- levels in HUVECs; decreases serum cholesterol, triglyceride, and phospholipid levels, the formation of TBARS, and vascular ACE activity in rabbits fed a high-cholesterol diet at 2 mg/kg per day; increases survival in a mouse model of myocardial infarction at 10 mg/kg per day
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Cayman Chemical MK886 sodium salt
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A potent FLAP antagonist that prevents 5-LO activation in vivo; inhibits LT biosynthesis in leukocytes with an IC50 value of 2.5 nM
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eMolecules 18386-03-3 | 3-(3-Bromo-phenoxy)-propionic acid | Combi-Blocks | MFCD00774355 | 245.072 | C9H9BrO3 | 95.000 | OC(=O)CCOc1cccc(Br)c1 | 1g | 117555346
3-(3-Bromo-phenoxy)-propionic acid | Combi-Blocks | 18386-03-3 | MFCD00774355 | 245.072 | C9H9BrO3 | 95.000 | OC(=O)CCOc1cccc(Br)c1 | 1g | 117555346
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Medchemexpress LLC Formate dehydrogenase | 9028-85-7 | 50 U
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Formate dehydrogenase is a class of oxidoreductases that catalyzes the reversible conversion between formic acid and carbon dioxide, involving redox reactions of coenzymes. This product is for research use only.
- Catalyzes reversible conversion of formic acid and carbon dioxide.
- Involves redox reactions of coenzymes like NAD+/NADH.
- Enhances tolerance to formic acid and acetic acid in Saccharomyces cerevisiae.
- Enhances aluminum tolerance in tobacco.
- Source: Pseudomonas syringae.
- Appearance: White to light yellow solid.
- Specific activity: ≥5 U/mg protein.
- Store at -20°C for 2 years.
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Medchemexpress LLC Suramin sodium salt | 129-46-4 | 100.0% | 25 MG
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Suramin sodium salt is a reversible and competitive protein-tyrosine phosphatases (PTPases) inhibitor. It also acts as a potent inhibitor of sirtuins (SirT1, SirT2, and SirT5) and a competitive inhibitor of reverse transcriptase (DNA topoisomerase II). Additionally, this agent is a potent SARS-CoV-2 RNA-dependent RNA polymerase (RdRp) inhibitor, efficiently inhibits IP5K, and functions as an antiparasitic, anti-neoplastic, and anti-angiogenic agent, intended for research use only.
- Reversible and competitive protein-tyrosine phosphatases (PTPases) inhibitor.
- Potent inhibitor of sirtuins (SirT1, SirT2, and SirT5).
- Competitive inhibitor of reverse transcriptase (DNA topoisomerase II).
- Potent SARS-CoV-2 RNA-dependent RNA polymerase (RdRp) inhibitor.
- Efficiently inhibits IP5K.
- Acts as an antiparasitic, anti-neoplastic, and anti-angiogenic agent.
- Intended for research use only.
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United States Biological Corporation Polymannuronic Acid, Sodium Salt CAS: 29894-36-8
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Sodium polymannuronate is produced from alginates by partial hydrolysis and chromatography of brown algae such as Laminaria digitata, Ascophyllum nodosum and Fucus spp. Food additive; anti-tumoral.
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Apexbio Technology LLC Concanavalin A (Con A)-FITC 5mg(5 mg/mL)
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Concanavalin A (Con A) derived from Canavalia ensiformis (jack bean) is a plant lectin protein with a molecular weight of approximately 104 kDa Each subunit can bind one Ca2 ion and one Mn2 ion and has one carbohydrate binding site Con A is capable of binding to various glycoproteins glycolipids and -D-glucose and -D-mannose residues FITC is a fluorescent dye that emits a green fluorescence under UV light (Ex/Em 495 nm/515 nm) This combination endows Con A-FITC with high visualization capability making it efficient for detecting carbohydrate molecules on the cell surface This product is FITC-labeled Con A in solution form It is applicable in glycobiology research serving as a probe to detect carbohydrate molecules on the cell surface and analyzed effectively using flow cytometry Applying IHC staining procedures with this product allows visualization of carbohydrate distribution in tissues or cells under a fluorescence microscope
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TARGETMOL CHEMICALS INC POPG sodium salt 25MG
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Also available in 5 mg, 10 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. POPG sodium salt is a phospholipid with a negative charge and is a component of biological membranes. It can be used to study the function of biological membranes.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000724142 LCC-12 FORMATE 1MG
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Apexbio Technology LLC Azlocillin sodium salt 37091-65-9 1g
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Azlocillin sodium salt (CAS 37091-65-9) is a small-molecule inhibitor targeting penicillin-binding proteins (PBPs) It is designed to inhibit bacterial cell wall synthesis thereby impeding cross-linking of peptidoglycan layers and inducing bacterial lysis Azlocillin sodium salt exerts its biological activity primarily through inhibition of PBPs disrupting cell wall integrity in bacteria In microbiological assays azlocillin demonstrates broad-spectrum antibacterial activity against both Gram-positive and Gram-negative bacteria reported IC50 values vary by microbial species and experimental conditions typically determined in minimum inhibitory concentration (MIC) assays Based on these pharmacological properties azlocillin sodium salt holds research potential in microbiological and biomedical investigations including studies of bacterial susceptibility resistance mechanisms and combinational antimicrobial therapies
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